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retroviral vector

Showing 1 - 25 of 841
STUDY
CONDITIONS
INTERVENTIONS
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Malignant Tumor Trial in Los Angeles (biological, drug, other, radiation, procedure)

Active, not recruiting
  • Malignant Neoplasm
  • aldesleukin
  • +7 more
  • Los Angeles, California
    University of California at Los Angeles (UCLA )
Dec 1, 2022

Epidermolysis Bullosa Dystrophica, Recessive Trial in Paris (COL7A1-SIN retroviral vector engineered autologous

Active, not recruiting
  • Epidermolysis Bullosa Dystrophica, Recessive
  • COL7A1-SIN retroviral vector engineered autologous tissue-engineered skin
  • Paris, France
    Institut Imagine Necker Hospital
Oct 18, 2021

Glioblastoma Multiforme Trial in Cleveland (biological, drug, other, procedure, radiation)

Active, not recruiting
  • Glioblastoma Multiforme
  • MGMTP140K-encoding retroviral vector
  • +6 more
  • Cleveland, Ohio
    University Hospitals Cleveland Medical Center, Case Comprehensiv
May 6, 2022

Pancreatic Cancer, Osteosarcoma, MPNST (Malignant Peripheral Nerve Sheath Tumor) Trial in Santa Monica (DeltaRex-G)

Available
  • Pancreatic Cancer
  • +6 more
  • Santa Monica, California
    Sarcoma Oncology Research Center, LLC
Jan 20, 2022

X-linked Severe Combined Immunodeficiency Trial in Paris (Gene transfer)

Completed
  • X-linked Severe Combined Immunodeficiency
  • Gene transfer
  • Paris, France
    Hopital Necker
Sep 22, 2021

Junctional Epidermolysis Bullosa Trial in Salzburg (Transplantation surgery of genetically corrected cultured epidermal

Terminated
  • Junctional Epidermolysis Bullosa
  • Transplantation surgery of genetically corrected cultured epidermal autograft (ATMP)
  • Salzburg, Austria
    EB House Austria, Department of Dermatology, Paracelsus Medical
Feb 18, 2022

Recessive Dystrophic Epidermolysis Bullosa Trial in Salzburg (Genetically corrected cultured epidermal autograft (ATMP))

Terminated
  • Recessive Dystrophic Epidermolysis Bullosa
  • Genetically corrected cultured epidermal autograft (ATMP)
  • Salzburg, Austria
    EB House Austria, Department of Dermatology, Paracelsus Medical
Feb 15, 2022

HIV Trial in Sacramento, San Francisco (drug, biological, other)

Recruiting
  • HIV Infections
  • Sacramento, California
  • +1 more
May 17, 2022

Ovarian Cancer, Endometrial Cancer Trial (Retroviral vector-transduced autologous T cells to express anti-ALPP CARs)

Not yet recruiting
  • Ovarian Cancer
  • Endometrial Cancer
  • Retroviral vector-transduced autologous T cells to express anti-ALPP CARs
  • (no location specified)
Nov 11, 2020

Newly Diagnosed High Grade Glioma (HGG) Trial (Toca 511, Toca FC)

Withdrawn
  • Newly Diagnosed High Grade Glioma (HGG)
  • Toca 511
  • Toca FC
  • (no location specified)
Mar 26, 2020

Chronic Granulomatous Disease Trial in Seoul (VM106)

Unknown status
  • Chronic Granulomatous Disease
  • Seoul, Korea, Republic of
    Seoul National University Hospital
Oct 16, 2019

Bladder Cancer Trial (Toca 511, Toca FC (extended-release formulation of flucytosine))

Withdrawn
  • Bladder Cancer
  • Toca 511
  • Toca FC (extended-release formulation of flucytosine)
  • (no location specified)
Mar 26, 2020

HIV Trial in Philadelphia (Autologous CD4+ T cells genetically modified with a retroviral vector expressing the MazF

Completed
  • HIV
  • Autologous CD4+ T cells genetically modified with a retroviral vector expressing the MazF endoribonuclease gene (MazF-T), given via intravenous infusion.
  • Philadelphia, Pennsylvania
    Division of Infectious Diseases & HIV Medicine at Drexel Univers
Aug 29, 2019

Anaplastic Astrocytoma, Glioblastoma, Oligodendroglioma Trial (drug, device, other, radiation, procedure, biological)

Withdrawn
  • Anaplastic Astrocytoma
  • +3 more
  • Extended Release Flucytosine
  • +7 more
  • (no location specified)
Mar 20, 2020

Colorectal Cancer, Triple Negative Breast Cancer, Pancreatic Cancer Trial in Denver, Miami, Houston (Toca 511, Toca FC)

Terminated
  • Colorectal Cancer
  • +11 more
  • Toca 511
  • Toca FC
  • Denver, Colorado
  • +2 more
Feb 5, 2020

Retroviral Insertion Site Analysis in Strimvelis Gene Therapy

Enrolling by invitation
  • Severe Combined Immunodeficiency Due to ADA Deficiency
  • Retroviral Insertion Site Analysis
  • Milan, Italy
    Ospedale San Raffaele - Telethon Institute for Gene Therapy (OSR
Feb 17, 2022

Post-transplant Lymphoproliferative Disease, Transplant-Related Hematologic Malignancy Trial in London (Autologous EBV-CTL

Active, not recruiting
  • Post-transplant Lymphoproliferative Disease
  • Transplant-Related Hematologic Malignancy
  • Autologous EBV-CTL transduced with vector SFG-CNA12
  • +2 more
  • London, United Kingdom
  • +1 more
Jan 19, 2022

Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Lymphoma Trial in United States (biological, drug, procedure)

Active, not recruiting
  • Acute Lymphoblastic Leukemia
  • +3 more
  • BPX-501 dose 1
  • +5 more
  • Atlanta, Georgia
  • +7 more
Jul 10, 2022

Glioma of Spinal Cord, Glioma of Brainstem Trial in Stanford (GD2 CAR T cells, Fludarabine, Cyclophosphamide)

Recruiting
  • Glioma of Spinal Cord
  • Glioma of Brainstem
  • GD2 CAR T cells
  • +2 more
  • Stanford, California
    Lucile Packard Children's Hospital (LPCH)
Jun 22, 2022

Lymphoblastic Leukemia, Acute Adult Trial in Japan (TBI-1501)

Active, not recruiting
  • Lymphoblastic Leukemia, Acute Adult
  • TBI-1501
  • Yoshida, Fukui, Japan
  • +10 more
Jun 15, 2022

Relapsed or Refractory CD19+ B-cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small

Recruiting
  • Relapsed or Refractory CD19+ B-cell Lymphoma
  • +2 more
  • TBI-2001
  • +2 more
  • Toronto, Ontario, Canada
    Princess Margaret Cancer Centre
Jul 26, 2023

Renal Cancer, Kidney Cancer Trial run by the NCI (2G-1 TCR Retroviral Vector-Transduced lyn, Aldesleukin, Cyclophosphamide)

Terminated
  • Renal Cancer
  • Kidney Cancer
  • 2G-1 TCR Retroviral Vector-Transduced lyn
  • +4 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
Apr 6, 2019

Severe Combined Immunodeficiency Trial in Los Angeles (ADA gene transfer)

Completed
Has Results
  • Severe Combined Immunodeficiency
  • ADA gene transfer
  • Los Angeles, California
    University of California, Los Angeles
Apr 21, 2021

Light Chain (AL) Amyloidosis Trial in Sacramento (NXC-201 CAR-T)

Not yet recruiting
  • Light Chain (AL) Amyloidosis
  • NXC-201 CAR-T
  • Sacramento, California
    University of California Davis Medical Center
Oct 19, 2023

Severe Combined Immunodeficiency Due to ADA Deficiency Trial in Milan (STRIMVELIS)

Completed
  • Severe Combined Immunodeficiency Due to ADA Deficiency
  • Milan, Italy
    Ospedale San Raffaele - Telethon Institute for Gene Therapy (OSR
Feb 18, 2022